j peptide science
ANDREW D. HUBERMAN: In advance of we start, I would like to emphasize this podcast is separate from my teaching and research roles at Stanford.
ANDREW D. HUBERMAN: Okay, so let us talk about particular peptides for certain functions. Now, We will cover 4 basic locations during which peptide therapeutics may be helpful.
ANDREW D. HUBERMAN: Other times They can be created by a compounding pharmacy, but in both of those circumstances, They may be cleaned of what's termed Lipopolysaccharide or LPS.
ANDREW D. HUBERMAN: And for that motive, I am going to mention some cautionary notes about BPC-157 because it relates to tumor growth and cancers and health conditions. Specifically of the eye that entail overgrowth of vasculature. But right before I do that, I wish to talk a bit with regards to the safety of BPC-157.
ANDREW D. HUBERMAN: Just to provide you with a little bit of background, try to remember the pituitary? The pituitary gland, that stock that extends out of your brain and will launch growth hormone from the anterior pituitary, very well, it's received a middle segment or even a medial segment. And there is a hormone which is released from there termed melanocyte-stimulating hormone.
ANDREW D. HUBERMAN: Lots of the peptide suppliers which have been on the market and physicians that are working with peptides will Blend diverse growth hormone endorsing peptides.
ANDREW D. HUBERMAN: Oxytocin, which is usually known as the enjoy hormone, although I wouldn't say that is the best description of what oxytocin is. It's a neuropeptide slash hormone that is definitely associated with all the things from pair bonding to socialization, but a lot of other factors in addition.
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ANDREW D. HUBERMAN: They are endeavoring to block the cispeptin pathway as a way to lessen a few of the vasomotor and also other indications of menopause. I will say, even though the cispeptin pathway is well known, and despite the fact that the cispeptin peptide is intended to mimic a By natural means happening peptide that has a pretty constrained set of functions, from the hypothalamic pituitary technique.
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ANDREW D. HUBERMAN: They just take it every day they usually'll just just take it indefinitely without any breaks. I imagine that is a bad strategy. And that i desire to also state that i'm not suggesting any individual operate out and choose BPC-157.
ANDREW D. HUBERMAN: And below, there is really no formal science. I want to be seriously apparent. When we discuss BPC-157, we can seem to a fairly huge literature of peer-reviewed studies relationship again to about 1993 is when the primary sort of demanding review of BPC-157 genuinely started.
ANDREW D. HUBERMAN: In any scenario, Cermorelin has been demonstrated to mimic what is Ordinarily produced from the hypothalamus and stimulates the pituitary to release growth hormone. And it does in fact result in improves in circulating growth hormone and raises in IGF-one.
ANDREW D. HUBERMAN: Now, if you start combining various peptides collectively, you have what's named polypeptides. And most of the proteins in your body are polypeptides. So just to secure a psychological impression of what a peptide is, a peptide basically appears like beads with a string.